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Analysis of Depression and Anxiety Scores Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Adults With Cystic Fibrosis.

Harish PudukoduMargret Z PowellAgathe CeppeScott H DonaldsonJennifer L GoralskiNathaniel A Sowa
Published in: The clinical respiratory journal (2024)
Treatment with E/T/I does not lead to changes in depression or anxiety symptoms at the population level in this single center cohort study. A prior diagnosis of depression trended towards an increased odds of worsening PHQ-9 scores after E/T/I initiation.
Keyphrases
  • sleep quality
  • depressive symptoms
  • cystic fibrosis
  • combination therapy