Severe and fatal COVID-19 is characterized by increased circulating GLP-1 and PCT and modulated by T2D.

Olga BlochKobi PerlAriel Ben ShimolAssaf RotmenshDana KaganskyDana Zelnik-YovelGilad Ben YehudahDror CantrellMicha J Rapoport

Published in: Diabetes/metabolism research and reviews (2023)

The persistent joint increase of endogenous GLP-1 and PCT in severe and fatal COVID-19 suggests a role of concomitant bacterial infection in disease exacerbation. Early elevation of endogenous GLP-1 may serve as new biomarker of COVID-19 severity and fatal outcome. This article is protected by copyright. All rights reserved.

Keyphrases

coronavirus disease
sars cov
early onset
chronic obstructive pulmonary disease
respiratory syndrome coronavirus
intensive care unit
acute respiratory distress syndrome