A role for primary cilia in aortic valve development and disease.

Katelynn A ToomerDiana FulmerLilong GuoAlex DrohanNeal PetersonPaige SwansonBrittany BrooksRupak MukherjeeSimon BodyJoshua H LipschutzAndy WesselsRussell A Norris

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2017)

Our data support cilia as a novel cellular mechanism for restraining ECM production during aortic valve development and broadly implicate these structures in the etiology of BAV disease in humans. Developmental Dynamics 246:625-634, 2017. © 2017 Wiley Periodicals, Inc.

Keyphrases

aortic valve
transcatheter aortic valve replacement
transcatheter aortic valve implantation
aortic valve replacement
aortic stenosis
high resolution
electronic health record
heart failure
coronary artery disease
left ventricular
deep learning