Impairment of body mass reduction-associated activation of brown/beige adipose tissue in patients with type 2 diabetes mellitus.
S RodovalhoB RachidJ C De-Lima-JuniorS van de Sande-LeeJ MorariH M CarvalhoB J AmorimA J TincaniE ChaimJ C ParejaM J SaadFranco FolliC D RamosBruno GelonezeLicio Augusto VellosoPublished in: International journal of obesity (2005) (2017)
Body mass reduction has a more efficient effect to induce the activation of B/BAT in non-diabetic than in diabetic subjects. This effect is accompanied by more pronounced insulin sensitivity and serine 473 phosphorylation of Akt in B/BAT of non-diabetic than in diabetic subjects.