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Relevance, strategies, and added value of mouse models in androgenetics.

Vertika SinghJohn C Schimenti
Published in: Andrology (2024)
These ongoing studies in mice have made an enormous contribution to our understanding of the genetics of human reproduction in the sense that the "parts list" of genes for mammalian gametogenesis is being elucidated. This would have been impossible to do in humans, and in vitro systems are not yet adequate to associate genes with andrological phenotypes, especially in the germline.
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