Impact of Tafamidis and Optimal Background Treatment on Physical Performance in Patients With Transthyretin Amyloid Cardiomyopathy.
Roza Badr EslamBegüm ÖztürkRené RettlChristophe Denis Josef CapelleHong QinChristina BinderTheresa-Marie DachsLuciana Camuz LigiosFranz DucaDaniel DalosLore SchrutkaFarideh AlastiJohannes KastnerGreisa VilaDiana BondermanPublished in: Circulation. Heart failure (2022)
and baseline minute ventilation/carbon dioxide production slope predict outcomes and an improvement in physical performance as measured by CPET was observed in patients receiving tafamidis, who had less advanced disease at baseline, emphasizing the importance of early diagnosis.