Metabolomic Biomarkers in Blood Samples Identify Cancers in a Mixed Population of Patients with Nonspecific Symptoms.

James R LarkinSusan AnthonyVanessa A Johanssen Tianrong YeoMegan SealeyAbi G YatesClaire Friedemann Smith Timothy D W ClaridgeBrian D NicholsonJulie-Ann MorelandFergus GleesonNicola R Sibson Daniel Clive AnthonyFay Probert

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

For a mixed group of patients referred from primary care with nonspecific signs and symptoms, NMR-based metabolomics can assist their diagnosis, and may differentiate both those with malignancies and those with and without metastatic disease. See related commentary by Van Tine and Lyssiotis, p. 1477.

Keyphrases

primary care
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
small cell lung cancer
magnetic resonance
mass spectrometry
peritoneal dialysis
high resolution
prognostic factors
sleep quality
depressive symptoms
patient reported outcomes
patient reported