Higher obesity class is associated with more severe esophageal symptoms and reflux burden but not altered motor function or contractile reserve.

Brent HiramotoWalker D ReddMayssan MuftahSaikiran JonnadulaNoreen C OkwaraAndrew JenkinsEliza Cricco-LizzaDarren J H LeeJennifer X CaiWalter Wai-Yip Chan

Published in: Neurogastroenterology and motility (2023)

Obesity is associated with increased esophageal symptom burden and worse physical HR-QOL, which correlate with higher acid/bolus reflux burden but not altered esophageal motility/transit/contractile reserve.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
skeletal muscle
type diabetes
high fat diet induced
weight gain
risk factors
smooth muscle
mental health
physical activity
early onset
body mass index
biofilm formation
sleep quality