METTL3 promoted ribosome biogenesis and oxidative phosphorylation by activating Wnt/β-catenin/c-Myc signaling in LPS-treated osteoblasts and alleviated the inflammatory alveolar bone destruction in periodontitis mice.
Keyphrases
- cell proliferation
- bone regeneration
- inflammatory response
- bone mineral density
- signaling pathway
- stem cells
- epithelial mesenchymal transition
- high fat diet induced
- oxidative stress
- anti inflammatory
- soft tissue
- protein kinase
- mouse model
- skeletal muscle
- adipose tissue
- insulin resistance
- metabolic syndrome
- quality control