Robotic System for MRI-guided Focal Laser Ablation in the Prostate.
Yue ChenAlexander SquiresReza SeifabadiSheng XuHarsh AgrawalMarcelino BernardoPeter PintoPeter ChoykeBradford WoodZion Tsz Ho TsePublished in: IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division (2016)
MRI-conditional robotic platforms have proved to be an effective approach for image guided interventions. In this study, a computer-assisted, pneumatically-actuated robot was designed, built, and tested for MRI-guided prostate cancer focal laser ablation (FLA). The robotic manipulator provides two active planar degrees of freedom (DoFs) by using a customized CoreXY frame, and one passive rotational DoF. A remote insertion mechanism improves the surgical workflow by keeping the patients inside the scanner during needle insertion. The robotic manipulator was tested in a 3T MR scanner to evaluate its MR compliance, and the results demonstrated that the signal-to-noise ratio (SNR) variation was less than 8%. The in-scanner template positioning accuracy test demonstrated that the manipulator achieves high targeting accuracy with a mean error of 0.46 mm and a standard deviation of 0.25mm. Phantom studies have shown that the needle insertion accuracy of the manipulator is within 2mm (Mean = 1.7mm, StD = 0.2mm).
Keyphrases
- contrast enhanced
- prostate cancer
- magnetic resonance imaging
- minimally invasive
- robot assisted
- image quality
- diffusion weighted imaging
- end stage renal disease
- magnetic resonance
- computed tomography
- ultrasound guided
- radical prostatectomy
- ejection fraction
- newly diagnosed
- high resolution
- peritoneal dialysis
- air pollution
- drug delivery
- dual energy
- monte carlo
- molecularly imprinted
- case control