Computed Tomographic Changes in Patients with Cystic Fibrosis Treated by Combination Therapy with Lumacaftor and Ivacaftor.

François ArnaudNathalie Stremler-Le BelMartine Reynaud-GaubertMancini JulienJean-Yves GaubertGuillaume Gorincour

Published in: Journal of clinical medicine (2021)

Treatment with lumacaftor-ivacaftor was associated with a significant improvement in the total CT score, which was mainly related to an improvement in mucous pluggings.

Keyphrases

cystic fibrosis
combination therapy
pseudomonas aeruginosa
lung function
computed tomography
contrast enhanced
image quality
magnetic resonance imaging
dual energy
positron emission tomography
chronic obstructive pulmonary disease
drug induced