Molecular cloning and characterization of the family of feline leucine-rich glioma-inactivated (LGI) genes, and mutational analysis in familial spontaneous epileptic cats.

Yoshihiko YuDaisuke HasegawaAki Fujiwara-IgarashiYuji HamamotoShunta MizoguchiTakayuki KuwabaraMichio Fujita

Published in: BMC veterinary research (2017)

We cloned the cDNAs of the four feline LGI genes, analyzed the amino acid sequences, and revealed that epilepsy in FSEC is not a monogenic disorder associated with LGI genes.

Keyphrases

genome wide
bioinformatics analysis
genome wide identification
amino acid
genome wide analysis
early onset
transcription factor
single molecule
genetic diversity