Comparison of preadministered and coadministered lidocaine for treating pain and distress associated with intranasal midazolam administration in children: A randomized clinical trial.

Nicole C O'ConnellHilary A WoodwardPamela L Flores-SanchezSon H McLarenMaria IeniKenneth W McKinleySripriya T ShenPeter S DayanDaniel S Tsze

Published in: Journal of the American College of Emergency Physicians open (2020)

Pain and distress associated with intranasal midazolam administration were similar when using coadministered or preadministered lidocaine, but our non-inferiority determination was inconclusive. Administration of intranasal lidocaine by itself was associated with a measurable degree of pain and distress.Keywords: intranasal, midazolam, anxiolysis, sedation, emergency department, emergency medicine, pain, distress, pediatric, lidocaine, laceration.

Keyphrases

chronic pain
emergency department
pain management
neuropathic pain
emergency medicine
young adults
intensive care unit
spinal cord
postoperative pain
mechanical ventilation
adverse drug
acute respiratory distress syndrome