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Efficacy of lower doses of pioglitazone after stroke or transient ischaemic attack in patients with insulin resistance.

J David SpenceCatherine ViscoliWalter N KernanLawrence H YoungKaren FurieMuhammad Abdul-GhaniMuhammad A Abdul-GhaniParesh DandonaCatherine M Viscoli
Published in: Diabetes, obesity & metabolism (2022)
Lower doses of pioglitazone appear to confer much of the benefit with less adverse effects than the full dose. Further study is needed to confirm these findings so that clinicians may optimize dosing of this secondary prevention strategy in patients with stroke.
Keyphrases
  • insulin resistance
  • atrial fibrillation
  • type diabetes
  • adipose tissue
  • cerebral ischemia
  • high fat diet
  • weight loss