Valproic acid induced selective apoptosis of ocular fibrous tunic in mice fetuses.
Kyriakos ManthosPaschalis TheotokisIasonas DermitzakisEleni AvramidouSoultana Meditskou-EythymiadouManthou Maria EleniElpida-Niki Emmanouil-NikoloussiPublished in: Birth defects research (2022)
Since the evaluation of the inner structures did not manifest major differences, we conclude that VPA teratogenic influence display eclectic toxicity, as seen by increased apoptosis to eye layers with high degree fibrous context, particularly the outer tunics.