Associations between early changes in the neutrophil-to-lymphocyte ratio after radical nephroureterectomy and treatment outcomes.
Shun SaitoHidetsugu TakahashiYuji YataShigeyoshi TakamizawaShuhei HaraKeiichiro MiyajimaKosuke IwataniKeiji YasueHideomi NishikawaToshihiro YamamotoHaruhisa KoideIbuki SadakaneMahito AtsutaKeiichiro MoriYu ImaiSotaro KayanoMasaya MurakamiKojiro TashiroShunsuke TsuzukiHiroki YamadaJun MikiNobuyoshi KosakaTakahiro Kimuranull On Behalf Of Jikei-Scrum Collaborative GroupPublished in: Japanese journal of clinical oncology (2024)
This is the first study to evaluate the association between peri-operative changes in the NLR and the outcomes of patients with UTUC who underwent radical nephroureterectomy. Patients with elevated NLRs at both time points experienced considerably worse outcomes. Further research should explore whether increases in the NLR during long-term follow-up could indicate impending disease recurrence.