Patterns of olfactory dysfunction in chronic rhinosinusitis identified by hierarchical cluster analysis and machine learning algorithms.
Justin C MorseMeghan H ShiltsKim A ElyPing LiQuanhu ShengLi-Ching HuangTodd J WannemuehlerNaweed I ChowdhuryRakesh K ChandraSuman R DasJustin H TurnerPublished in: International forum of allergy & rhinology (2018)
Olfactory dysfunction is associated with specific CRS endotypes characterized by severe nasal polyposis, tissue eosinophilia, and AERD. Mucus IL-2 levels, CT score, and AERD were independently associated with smell loss.