Implantable Devices for the Treatment of Breast Cancer.
Mohammad Mohtasim Hamid PialAsahi TomitakaNezih PalaUpal RoyPublished in: Journal of nanotheranostics (2022)
Breast cancer is one of the leading causes of death in the female population worldwide. Standard treatments such as chemotherapy show noticeable results. However, along with killing cancer cells, it causes systemic toxicity and apoptosis of the nearby healthy cells, therefore patients must endure side effects during the treatment process. Implantable drug delivery devices that enhance therapeutic efficacy by allowing localized therapy with programmed or controlled drug release can overcome the shortcomings of conventional treatments. An implantable device can be composed of biopolymer materials, nanocomposite materials, or a combination of both. This review summarizes the recent research and current state-of-the art in these types of implantable devices and gives perspective for future directions.
Keyphrases
- drug delivery
- drug release
- cell cycle arrest
- oxidative stress
- end stage renal disease
- chronic kidney disease
- cell death
- high resolution
- prognostic factors
- endoplasmic reticulum stress
- mesenchymal stem cells
- radiation therapy
- signaling pathway
- young adults
- squamous cell carcinoma
- replacement therapy
- combination therapy
- pi k akt
- solid phase extraction
- current status
- highly efficient