Acute Heart Failure Is a Malignant Process: But We Can Induce Remission.
Gad CotterBeth A DavisonCarolyn S P LamMarco MetraPiotr PonikowskiJohn R TeerlinkAlexandre MebazaaPublished in: Journal of the American Heart Association (2023)
Acute heart failure is a common and increasingly prevalent condition, affecting >10 million people annually. For those patients who survive to discharge, early readmissions and death rates are >30% everywhere on the planet, making it a malignant condition. Beyond these adverse outcomes, it represents one of the largest drivers of health care costs globally. Studies in the past 2 years have demonstrated that we can induce remissions in this malignant process if therapy is instituted rapidly, at the first acute heart failure episode, using full doses of all available effective medications. Multiple studies have demonstrated that this goal can be achieved safely and effectively. Now the urgent call is for all stakeholders, patients, physicians, payers, politicians, and the public at large to come together to address the gaps in implementation and enable health care providers to induce durable remissions in patients with acute heart failure.
Keyphrases
- acute heart failure
- healthcare
- heart failure
- end stage renal disease
- primary care
- ejection fraction
- chronic kidney disease
- prognostic factors
- case control
- peritoneal dialysis
- mental health
- patient reported outcomes
- systemic lupus erythematosus
- quality improvement
- mesenchymal stem cells
- disease activity
- health information
- replacement therapy
- electronic health record