Interleukin-6 pathobiology in equine placental infection.
Carleigh Elizabeth FedorkaKirsten E ScogginHossam El-Sheikh AliShavahn C LouxPouya DiniMats H T TroedssonBarry A BallPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2021)
IL-6 plays a crucial role in the placental response to induction of sub-acute equine ascending placentitis, and this could be noted in amniotic fluid, allantoic fluid, and maternal serum. Additionally, IL-6 is acting as anti-inflammatory in this disease, potentially altering disease progression, impeding abortion signals, and assisting with the production of a viable neonate.