Venous injection of a triphasic calcium-based implant in a sheep model of pulmonary embolism demonstrates minimal acute systemic effects.
Caroline ConstantJohn D StroncekStephan ZeiterDaniel ArensDirk NehrbassDominic GehweilerUrsula MenzelLorin M BennekerRonald S HillChristoph Emanuel AlbersPublished in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2022)
Acute systemic effects of intravascular AGN1 appeared to be comparable to or less than that of intravascular PMMA. Furthermore, in this preliminary study, the severity and incidence of pulmonary histological changes were lower for AGN1 compared to PMMA.