Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10.

Stacy GrieveKeyue DingJonathan MooreMathew FinnissAyush RayMiranda LeesFaisal HossainAlli MurugesanJane AgarCenk AcarJames TaylorFrances A ShepherdAnthony Reiman

Published in: ESMO open (2021)

Zhu's GEP could not be translated into an IHC panel predictive of benefit from adjuvant chemotherapy. Future predictive biomarker analysis in the adjuvant NSCLC setting may need to focus on novel therapies.

Keyphrases

small cell lung cancer
early stage
lymph node
copy number
current status
genome wide
dna methylation
prognostic factors
tyrosine kinase