Para-Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes.
Michael BergerMarola S LenhardSiegfried R WaldvogelPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2022)
The para-selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF 2 is reported, with Et 3 N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set-up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %.