Systematic thyroid screening in myotonic dystrophy: link between thyroid volume and insulin resistance.

Adrien Ben HamouStéphanie EspiardChristine Do CaoMiriam LadsousCamille LoyerAlexandre MoermanSamuel BouryMaéva KyhengClaire-Marie DhaenensVincent TiffreauPascal PignyGilles LebuffeRobert CaiazzoSébastien AubertMarie-Christine Vantyghem

Published in: Orphanet journal of rare diseases (2019)

In this systematically screened DM1 cohort, the frequency of UsGoiter, mainly associated to BMI, was about 40%, US nodules 60%, thyroidectomies 13-14%, and PTCs 8%, two-thirds of them being micro-PTCs with good prognosis. Therefore, a systematic screening remains debatable. A targeted US screening in case of clinical abnormality or high BMI seems more appropriate.

Keyphrases

body mass index
type diabetes
metabolic syndrome
insulin resistance
glycemic control