Race influences survival in glioblastoma patients with KPS ≥ 80 and associates with genetic markers of retinoic acid metabolism.
Meijing WuJason MiskaTing XiaoPeng ZhangJ Robert KaneIrina V BalyasnikovaJames P ChandlerCraig M HorbinskiMaciej S LesniakPublished in: Journal of neuro-oncology (2019)
African Americans have prolonged survival with glioma which is influenced only by initial KPS score. Genes previously associated with both racial disparities in cancer and pathways associated with RA metabolism may play an important role in glioma etiology. In the future exploration of these genes and pathways may inform novel therapies for this incurable disease.
Keyphrases
- genome wide
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- affordable care act