Dimethyl Fumarate Reduces Inflammation in Chronic Active Multiple Sclerosis Lesions.

Nicole ZingerGerald PonathElizabeth SweeneyThanh D NguyenChih Hung LoIvan DiazAlexey V DimovLeilei TengLily ZexterJoseph ComunaleYi WangDavid Pitt Susan A Gauthier

Published in: Neurology(R) neuroimmunology & neuroinflammation (2022)

This study provided Class III evidence that DMF is superior to GA in the presence of iron as a marker of inflammation as measured by MRI quantitative susceptibility mapping.

Keyphrases

multiple sclerosis
oxidative stress
high resolution
pet ct
magnetic resonance imaging
contrast enhanced
high density
white matter
mass spectrometry
diffusion weighted imaging
iron deficiency