Modified Messengers: flatworm stem cells and regeneration are guarded by RNA methylation.

Published in: The EMBO journal (2022)

The contribution of RNA modifications to whole-body regeneration remains unclear. In this issue, Dagan et al (2022) show that m6a mRNA pathway components are critically required for stem cell differentiation, survival, and tissue renewal in the planarian Schmidtea mediterranea.

Keyphrases

stem cells
cell therapy
nucleic acid
genome wide
gene expression
mesenchymal stem cells