Development and implementation of ISAR, a new synthesis platform for radiopharmaceutical production.
Christopher FrankGeorg WinterFredrik RenseiVictor SamperAllen F BrooksBrian G HockleyBradford D HendersonChristian RenschPeter J H ScottPublished in: EJNMMI radiopharmacy and chemistry (2019)
ISAR represents a new paradigm in radiopharmaceutical production. Through a new system architecture, ISAR integrates the principles of microfluidics with the standard volumes and consumables established in PET Centers all over the world. Proof-of-concept has been demonstrated through validation of a chip design for the synthesis of [13N]NH3 suitable for clinical use.