Update on the oncologic and obstetric outcomes of medroxyprogesterone acetate treatment for atypical endometrial hyperplasia and endometrial cancer.
Satoshi TamauchiAtsushi NakagawaKosuke YoshidaMasato YoshiharaAkira YokoiNobuhisa YoshikawaKaoru NiimiHiroaki KajiyamaPublished in: The journal of obstetrics and gynaecology research (2024)
High-dose oral MPA therapy demonstrated both safety and efficacy for preserving fertility in patients with AEH and G1EC, resulting in a high CR rate. MPA extension and readministration proved to be beneficial strategies for managing patients with recurrence and persistent disease following initial treatment.