Propofol and salvianolic acid A synergistically attenuated cardiac ischemia-reperfusion injury in diabetic mice via modulating the CD36/AMPK pathway.

Jiaqi ZhouWeiyi XiaJiajia ChenKaijia HanYuxin JiangAnyuan ZhangDongcheng ZhouDanyong LiuJiefu LinYin CaiGuanghua ChenLiangqing ZhangAimin XuYouhua XuRonghui HanZhengyuan Xia

Published in: Burns & trauma (2024)

Combinational usage of propofol and SAA confers superior cellular protective effects to the use of high-dose propofol alone, and it does so through inhibiting HR-induced CD36 overexpression to upregulate p-AMPK.

Keyphrases

high dose
signaling pathway
skeletal muscle
high glucose
low dose
nk cells
cell proliferation
diabetic rats
left ventricular
stem cell transplantation
drug induced
oxidative stress
atrial fibrillation