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Relationship between IGF-I Concentration and Metabolic Profile in Children with Growth Hormone Deficiency: The Influence of Children's Nutritional State as well as the Ghrelin, Leptin, Adiponectin, and Resistin Serum Concentrations.

Renata StawerskaJoanna SmyczyńskaMaciej HilczerAndrzej Lewiński
Published in: International journal of endocrinology (2017)
A better metabolic profile characterised GHD children with low IGF-I bioavailability. This phenomenon may be the result of high adiponectin and ghrelin concentrations in those children and their influence on adipose tissue, glucose uptake, and orexigenic axis.
Keyphrases
  • growth hormone
  • young adults
  • adipose tissue
  • insulin resistance
  • metabolic syndrome
  • type diabetes
  • high fat diet
  • pi k akt
  • binding protein