Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinoma.
Julia R NasoJames T TophamJoanna M KarasinskaMichael Kuan-Ching LeeSteve E KallogerHui-Li WongJessica NelsonRichard A MooreAndrew J MungallSteven J M JonesJanessa LaskinMarco A MarraDaniel J RenoufDavid F SchaefferPublished in: Cancer medicine (2020)
The assessment of gland formation and neutrophil infiltration on routine histological sections can aid in prognostication and allow inferences to be made about molecular subtype, which may help guide patient management decisions and contribute to our understanding of heterogeneity in treatment response.