Plasma heat shock protein response to euglycemia in type 2 diabetes.
Alexander S AtkinAbu Saleh Md MoinAhmed Al-QaissiThozhukat SathyapalanStephen L AtkinAlexandra E ButlerPublished in: BMJ open diabetes research & care (2021)
Key HSPRPs involved in critical protein interactions, CHIP and UBE2G2, were altered in diabetes at baseline. DNAJB1 fell in response to euglycemia, suggesting that HSPs are reacting to basal stress that could be mitigated by tight glucose control with reduction of glucose variability.