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Novel TFG mutation causes autosomal-dominant spastic paraplegia and defects in autophagy.

Ling XuYaru WangWenqing WangRui ZhangDandan ZhaoYan YunFuchen LiuYuying ZhaoChuanzhu YanPengfei Lin
Published in: Journal of medical genetics (2023)
mutations. Consequently, targeting autophagy may facilitate the development of a uniform treatment for TFG-related neurological disorders.
Keyphrases
  • cell death
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress
  • cerebral palsy
  • botulinum toxin
  • upper limb
  • drug delivery
  • brain injury
  • subarachnoid hemorrhage