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Tacrolimus concentrations after renal transplantation in a mother-neonate dyad: Maternal, neonatal and breast milk measurements.

Yumiko AkamineNobuhiro FujiyamaHideaki KagayaMitsuru SaitoHiroshi MiuraYukihiro TeradaTsutomu TakahashiShigeru SatohMasatomo Miura
Published in: Journal of clinical pharmacy and therapeutics (2021)
The maternal and neonatal blood tacrolimus concentrations at birth are equivalent; thus, one must assume that maternal tacrolimus concentrations directly affect the foetus and/or neonate. Tacrolimus is not detectable in the neonate 3 weeks after birth, suggesting that there is minimal transfer through breast milk.
Keyphrases
  • birth weight
  • gestational age
  • pregnancy outcomes
  • preterm birth
  • pregnant women
  • physical activity
  • weight loss