Urea treatment in fluid restriction-refractory hyponatraemia.

Jack LockettKathryn E BerkmanGoce DimeskiAnthony W RussellWarrick J Inder

Published in: Clinical endocrinology (2019)

Urea is safe and effective in fluid restriction-refractory hyponatraemia. We recommend urea with a starting dose of ≥30 g/d, in patients with SIADH and moderate to profound hyponatraemia who are unable to undergo, or have failed fluid restriction.

Keyphrases

intellectual disability
high intensity
combination therapy
replacement therapy