Human decidua basalis mesenchymal stem/stromal cells protect endothelial cell functions from oxidative stress induced by hydrogen peroxide and monocytes.

M A AlshabibiT KhatlaniF M AbomarayA S AlAskarB KalionisS A MessaoudiR KhanabdaliA O AlawadM H Abumaree

Published in: Stem cell research & therapy (2018)

We conclude that DBMSCs have potential for therapeutic application in inflammatory diseases, such as atherosclerosis by protecting endothelial cells from oxidative stress damage. However, more studies are needed to elucidate this further.

Keyphrases

oxidative stress
endothelial cells
hydrogen peroxide
diabetic rats
ischemia reperfusion injury
nitric oxide
dna damage
high glucose
induced apoptosis
stem cells
cardiovascular disease
bone marrow
dendritic cells
vascular endothelial growth factor
peripheral blood
type diabetes
heat shock
climate change