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Reorganization of 3D genome architecture across wild boar and Bama pig adipose tissues.

Jiaman ZhangPengliang LiuMengnan HeYujie WangHua KuiLong JinDiyan LiMingzhou Li
Published in: Journal of animal science and biotechnology (2022)
We reported 3D genome organization in adipose depots from different pig breeds. In a comparison of Bama pigs and wild boar, large-scale compartments and TADs were mostly conserved, while fine-scale PEIs were extensively reorganized. The chromatin architecture in these two pig breeds was reorganized in an adipose depot-specific manner. These results contribute to determining the regulatory mechanism of phenotypic differences between Bama pigs and wild boar.
Keyphrases
  • genetic diversity
  • transcription factor
  • adipose tissue
  • insulin resistance
  • genome wide
  • gene expression
  • air pollution
  • dna damage
  • multidrug resistant
  • type diabetes
  • dna methylation
  • metabolic syndrome