Reorganization of 3D genome architecture across wild boar and Bama pig adipose tissues.
Jiaman ZhangPengliang LiuMengnan HeYujie WangHua KuiLong JinDiyan LiMingzhou LiPublished in: Journal of animal science and biotechnology (2022)
We reported 3D genome organization in adipose depots from different pig breeds. In a comparison of Bama pigs and wild boar, large-scale compartments and TADs were mostly conserved, while fine-scale PEIs were extensively reorganized. The chromatin architecture in these two pig breeds was reorganized in an adipose depot-specific manner. These results contribute to determining the regulatory mechanism of phenotypic differences between Bama pigs and wild boar.