Seizure reduction in TSC2-mutant mouse model by an mTOR catalytic inhibitor.
Sameer C DhamneMeera E ModiAudrey GraySimone BonazziLucas CraigElizabeth BainbridgeLahin LalaniChloe E SuperSamantha SchaefferKetthsy CapreDanuta LubickaGuiqing LiangDoug BurdetteStephanie M McTigheSarika GurnaniSheryl Anne D VermudezDaniel CurtisChristopher J WilsonMustafa Q HameedAngelica D'AmoreAlexander RotenbergMustafa SahinPublished in: Annals of clinical and translational neurology (2023)
Novel mTOR catalytic inhibitor TC1 exhibits a promising therapeutic option in the treatment of TSC.