Multi-Institutional Outcomes of Patients Aged 75 years and Older With Pancreatic Ductal Adenocarcinoma Treated With 5-Fraction Ablative Stereotactic Magnetic Resonance Image-Guided Adaptive Radiation Therapy (A-SMART).
John Michael BryantRussell F PalmRoberto HerreraAnshul SaxenaSarah E HoffeDae Won KimAdeel KaiserAntonio UcarJason FlemingFernando De ZarragaPamela HodulSantiago AparoHoracio AsbunMokenge MalafaRamon JimenezJason DenboJessica M FrakesMichael D ChuongPublished in: Cancer control : journal of the Moffitt Cancer Center (2023)
A-SMART is associated with encouraging LRC and OS in elderly patients with initially inoperable PDAC. This novel non-invasive treatment strategy appears to be well-tolerated in patients with advanced age and should be considered in this population that has limited treatment options.
Keyphrases
- magnetic resonance
- radiation therapy
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- middle aged
- community dwelling
- peritoneal dialysis
- prognostic factors
- type diabetes
- magnetic resonance imaging
- small cell lung cancer
- radiation induced
- combination therapy
- squamous cell carcinoma
- insulin resistance
- skeletal muscle
- smoking cessation
- brain metastases