FAM83A is a potential biomarker for breast cancer initiation.

Natascia MarinoRana GermanRam PodichetiPam RockeyGeorge E SanduskyConstance J TemmHarikrishna NakshatriRebekah J AddisonBryce SelmanSandra K AlthouseAnna Maria V Storniolo

Published in: Biomarker research (2022)

This study shows that FAM83A promotes metabolic activation in primary breast epithelial cells and cell proliferation in both primary and immortalized cells. These findings support its role in early breast oncogenesis.

Keyphrases

cell proliferation
induced apoptosis
cell cycle arrest
pi k akt
signaling pathway
cell death