Immune Activation Mediates the Association of Advanced Hepatic Fibrosis With Adverse Outcomes in Patients With Coronary Artery Disease.
Vardhmaan JainAnurag MehtaTerence B LeeChang LiuNicholas W S ChewYi-An KoMatthew E GoldDaniel A GoldNishant VatsaShivang R DesaiJonathan H KimAlireza RahbarYazan HarounKiran EjazSalim Salim HayekMohammad S SiddiquiFadi N SalloumLaurence S SperlingArun J SanyalArshed A QuyyumiPublished in: Journal of the American Heart Association (2023)
AHF is independently associated with immune activation, systemic inflammation, and adverse cardiovascular outcomes in patients with CAD. The association of AHF with adverse outcomes is partly mediated by immune activation, and targeting this pathway may help reduce the residual risk in patients with CAD.