Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study.
Manman GuoCemsel BafligilThomas TapmeierCarol HubbardSanjiv ManekCatherine ShangFernando O MartinezNicole SchmidtMaik ObendorfHolger Hess-StumppThomas M ZollnerStephen KennedyChristian M BeckerKrina T ZondervanAdam P CribbsUdo OppermannPublished in: BMC medicine (2020)
This study provides a systematic characterisation of the specific immune environment in the peritoneal cavity and identifies cell immune signatures associated with endometriosis. Overall, our results provide novel insights into the specific cell phenotypes governing inflammation in patients with endometriosis. This prospective study offers a useful resource for understanding disease pathology and opportunities for identifying therapeutic targets.