Appendectomy history is associated with severe disease and colchicine resistance in adult familial Mediterranean fever patients
Erdal BodakciNazife Şule Yaşar BilgeNuh AtasBerkan ArmağanHasan SatişAlper SariReyhan Bilici SalmanGözde Kübra YardimciHakan BabaogluLevent KilicMehmet Akif OzturkBerna GökerSeminur HaznedaroğluUmut KalyoncuAbdurrahman TufanTimucin KaşifogluPublished in: Turkish journal of medical sciences (2021)
Appendectomy history is common in FMF patients and associated with frequent serositis attacks in adulthood. These patients require higher colchicine doses with a lower rate of response and more need for Interleukin-1 antagonist therapies.