[FGF23 tumor induced osteomalacia with localization of neoplasm in the tympanic cavity].
A Yu OvchinnikovE M KhonAnna V BakotinaN A MiroshnichenkoSofia GronskayaZhanna BelayaPublished in: Vestnik otorinolaringologii (2024)
Tumor induced osteomalacia is a rare paraneoplastic syndrome caused by mesenchymal tumors that secrete fibroblast growth factor 23 (FGF23). Patients complain of progressive bone pain, muscle weakness and brittle fractures. Delayed diagnosis of osteomalacia caused by a tumor is often found in clinical practice. When verifying the exact localization of the neoplasm, radical removal within healthy tissues is recommended. The article considers a clinical example of FGF23 tumor induced osteomalacia with localization of neoplasm in the tympanic cavity.
Keyphrases
- high glucose
- diabetic rats
- clinical practice
- low grade
- end stage renal disease
- chronic pain
- stem cells
- multiple sclerosis
- drug induced
- endothelial cells
- newly diagnosed
- gene expression
- peritoneal dialysis
- prognostic factors
- skeletal muscle
- molecular dynamics
- pain management
- neuropathic pain
- case report
- patient reported outcomes