Involvement of IL-26 in bronchiolitis obliterans syndrome but not in acute rejection after lung transplantation.
Jesper M MagnussonPetrea EricsonSara TengvallMarit StockfeltBettina BrundinAnders LindénGerdt C RiisePublished in: Respiratory research (2022)
Local IL-26 seems to be involved in BOS but not AR, and macrophages as well as lymphocytes constitute cellular sources in this clinical setting. The enhancement of extracellular IL-26 protein in LTRs with BOS warrants further investigation of its potential as a target for diagnosing, monitoring, and treating BOS.