The experimental study of mir-99a-5p negative regulation of TLR8 receptor mediated-mediated innate immune response in rabbit knee cartilage injury.

Jiebin ZhangKe ZhengYichao WuShengting ZhangAo GuoCong Sui

Published in: Immunity, inflammation and disease (2024)

Based on the results from this study, mir-99a-5p may be an effective molecular marker for predicting traumatic cartilage injury and targeting TLR8 is a novel and promising approach for the prevention or early treatment of cartilage damage.

Keyphrases

innate immune
toll like receptor
extracellular matrix
inflammatory response
immune response
spinal cord injury
total knee arthroplasty
nuclear factor
knee osteoarthritis
cancer therapy