Significant disparities in allergy prevalence and microbiota between the young people in Finnish and Russian Karelia.
Lasse RuokolainenL PaalanenA KarkmanT LaatikainenL von HertzenT VlasoffO MarkelovaV MasyukP AuvinenL PaulinH AleniusN FyhrquistI HanskiM J MäkeläE ZilberP JousilahtiE VartiainenT HaahtelaPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
Differences in allergic phenotype, developed in early life, remain between populations. A parallel difference in the composition of skin and nasal microbiota suggests a potential underlying mechanism. Our results also suggest that high abundance and diversity of Acinetobacter might contribute to the low allergy prevalence in Russia. Implications of early-life exposure to Acinetobacter should be further investigated.