Usefulness of therapeutic drug monitoring of piperacillin and meropenem in routine clinical practice: a prospective cohort study in critically ill patients.
Joan Antoni Schoenenberger-ArnaizFaten Ahmad-DiazMar Miralbes-TornerAna Aragones-ErolesManuel Cano-MarronMercedes Palomar-MartinezPublished in: European journal of hospital pharmacy : science and practice (2019)
The results of the study show that, in critically ill patients with sepsis, there is a significant proportion of treatment courses where target levels are not reached even if the antibiotics are administered by CII and TDM support is provided by the pharmacy service. This TDM support should be offered on a real-time basis to be really useful.