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Obesity, transplantation, and bariatric surgery: An evolving solution for a growing epidemic.

Tayyab S DiwanTiffany C LeeShunji NagaiEnrico BenedettiAndrew PosseltGinny L BumgardnerSabrena NoriaBryan A WhitsonLloyd RatnerDavid MasonJon FriedmanKenneth J WoodsideJulie K Heimbach
Published in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons (2020)
The increasing obesity epidemic has major implications in the realm of transplantation. Patients with obesity face barriers in access to transplant and unique challenges in perioperative and postoperative outcomes. Because of comorbidities associated with obesity, along with the underlying end-stage organ disease leading to transplant candidacy, these patients may not even be referred for transplant evaluation, much less be waitlisted or actually undergo transplant. However, the use of bariatric surgery in this population can help optimize the transplant candidacy of patients with obesity and end-stage organ disease and improve perioperative and postoperative outcomes. We review the impact of obesity on kidney, liver, and cardiothoracic transplant candidates and recipients and explore potential interventions to address obesity in these populations.
Keyphrases
  • weight loss
  • insulin resistance
  • bariatric surgery
  • metabolic syndrome
  • high fat diet induced
  • type diabetes
  • weight gain
  • patients undergoing
  • adipose tissue
  • ejection fraction
  • newly diagnosed
  • human health